Q CLINICAL CASE REPORT Chapter 9 Running Problem: Infantile Spasms 1. How might a leaky blood-brain barrier lead to action potentials that trigger a seizure? 2. What does GABA do to the cell’s membrane potential? Does GABA make the cell more or less likely to fire action potentials? 3. Why is it important to limit the duration of ACTH therapy? 4. What is the rationale for using radioactively-labeled glucose (and not some other nutrient) for the PET scan? 5. ) The brain’s ability to change its synaptic connections as a result of neuronal activity is called